Mumbai: A personal story shared by Archana Puran Singh’s family has brought renewed focus to Complex Regional Pain Syndrome (CRPS), a rare neurological condition that specialists say can have long-lasting and sometimes irreversible effects on a person’s mobility and quality of life.
The discussion began after the actor’s son, Ayushmaan Sethi, posted a heartfelt message on social media praising his mother’s determination. In the post, he revealed that Archana was diagnosed with CRPS after suffering a wrist injury in 2025 while shooting for Vicky Vidya Ka Wo Wala Video. Although the injury itself healed, the condition left her with permanent impairment in her hand and ongoing pain.
Despite the physical challenges, Archana continued to remain professionally active. Ayushmaan noted that she pushed through intense discomfort to complete film projects, appear in a web series and even start her own YouTube channel in her early sixties — a decision he described as a reflection of her resilience.
Medical experts explain that CRPS is not a typical post-injury complication. According to clinical research referenced by the National Institutes of Health, the disorder occurs when the nervous system misfires, producing pain signals that are far stronger and longer-lasting than expected. Unlike ordinary injuries, the pain persists even after tissues have recovered.
Dr Neha Kapoor, Associate Director and Head of Neurology at Asian Hospital, explained that CRPS develops when the brain and spinal cord fail to regulate pain properly. “The condition is driven by abnormal communication within the nervous system,” she said. “Even when there is no ongoing physical damage, the nerves continue to send amplified pain messages, which can severely limit movement and function.”
Patients with CRPS often describe the pain as intense burning or sharp, electric-like sensations. Sensitivity becomes so heightened that mild touch, light pressure or changes in temperature can trigger severe discomfort. In addition, the affected limb may show visible changes such as swelling, unusual sweating, skin discolouration and temperature differences, all linked to disturbances in autonomic nerve function.
CRPS is broadly categorised into two forms. Type I appears without clear evidence of nerve damage, while Type II follows a confirmed nerve injury. Over time, both forms can lead to muscle wasting, joint stiffness and reduced mobility if left untreated.
Diagnosis relies largely on clinical judgment, as there is no definitive test for the condition. Doctors assess symptoms, conduct physical examinations and rule out other neurological or orthopaedic disorders. Imaging may support the process but cannot confirm CRPS on its own. Specialists stress that early detection significantly improves the chances of managing the condition effectively.
Treatment typically involves a combination of pain medication, physiotherapy to maintain movement and, in some cases, specialised pain-management procedures. Psychological support is also considered essential, as living with persistent pain can take a heavy emotional toll.
“CRPS may not be fatal, but it can change the course of a person’s life,” Dr Kapoor said. “The longer it remains untreated, the greater the risk of permanent damage. Awareness and timely medical intervention are critical.”
By speaking openly about her experience, Archana Puran Singh has helped draw attention to a disorder that often goes unrecognised, underscoring the importance of understanding chronic pain conditions and the strength required to live with them.
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